Filamentous Fungi in Respiratory Infections. What Lies Beyond Aspergillosis and Mucormycosis?

نویسندگان

  • Anuradha Chowdhary
  • Kshitij Agarwal
  • Jacques F Meis
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Fungal infections of the Respiratory Tract-Section 1

Fungal infections of the Respiratory Tract are important causes of morbidity and mortality in immunocompromised hospitalized patients. Among these patients are those receiving cytotoxic chemotherapy for neoplastic diseases, those undergoing bone marrow stem cell transplantation or organ transplantation, and those affected with the acquired immune deficiency syndrome. Invasive Aspergillosis has ...

متن کامل

Comparison of serum PCR assay and histopathology for the diagnosis of invasive aspergillosis and mucormycosis in immunocompromised patients with sinus involvement

Background and Purpose: Invasive fungal infections cause morbidity and mortality in patients with hematologic malignancies and immunosuppression. Although these infections are commonly caused by Candida and Aspergillus species, infections caused by Mucoralean fungi are also on a growing trend. The definitive diagnosis of mucormycosis includes visualization of non-septate hyphae on patholog...

متن کامل

Usefulness of molecular biology performed with formaldehyde-fixed paraffin embedded tissue for the diagnosis of combined pulmonary invasive mucormycosis and aspergillosis in an immunocompromised patient

Immunocompromised patients who develop invasive filamentous mycotic infections can be efficiently treated if rapid identification of the causative fungus is obtained. We report a case of fatal necrotic pneumonia caused by combined pulmonary invasive mucormycosis and aspergillosis in a 66 year-old renal transplant recipient. Aspergillus was first identified during the course of the disease by cy...

متن کامل

Isavuconazole: A New Broad-Spectrum Triazole Antifungal Agent.

Isavuconazole is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi. It is approved for the treatment of invasive aspergillosis and mucormycosis. Advantages of this triazole include the availability of a water-soluble intravenous formulation, excellent bioavailability of the oral formulation, and predictable pharmacokinetics in adults. A randomized, double...

متن کامل

How does antifungal pharmacology differ for mucormycosis versus aspergillosis?

Over the last decade, advances in diagnostic systems and the introduction of new antifungal agents have significantly improved outcomes in immunocompromised patients who develop invasive aspergillosis. However, mortality rates remain relatively unchanged for less common, but highly aggressive, mold infections such as mucormycosis. Recent genome sequencing of Rhizopus oryzae revealed evidence of...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • PLoS pathogens

دوره 12 4  شماره 

صفحات  -

تاریخ انتشار 2016